The traditional knowledge on medicinal plants is inherent in indigenous communities and important in the development of drugs and plant-based medicine as it lays down the foundation of drug discovery. Ethnobotanical survey using interviews and focused group discussions in the local community of Sablan, Benguet province revealed that there are 75 plants that belong to 68 genera and 43 families to have medicinal value. The leaves are predominantly used for the treatment of the various ailments. Decoction is the major mode of preparation for the cure of cough, kidney ailments, and stomach disorders such as diarrhea, ulcers and related ailments. In Benguet province, documentation of the claimed medicinal plants by local communities will not only provide a baseline data but also unlock opportunities for the discovery and development of new and less expensive plant-based medicines.