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Abstract

Antifungal Activities of Methanolic Extract of Plants

Using modern medicine is seriously proposed as a worldwide public health concern due to its adverse side effect problems, whereas the use of herbal drugs in fungal infections claimed to be not only effective but also safe and out of danger.Herbal medicine as an independent treatment way or alongside western medicine can be helpful for in treating fungal infections. Curcuma longa L. (Zingiberaceae family) and Quercus sessilifolia (Fagaceae family) have been noticed in a variety of antifungal investigations due to extensive traditional uses and low side effects. This paper attempts to show that for the first time the effect of two plant extracts against fungi was studied. Antifungal activities of methanolic extract of plants were evaluated against pathogens (Trichophyton mentagrophytes, Epidermophyton floccosum, Microsporum canis) fungi with pourplate method (50, 25, 12.5, 6.2, 3.1, 1.5 mg ml-1 extract in medium). Concentration of clotrimazol as a control was 10 μg.ml-1. The results indicated that plant extracts prevent the growth of dermatophytes fungi. The foremost inhibitory effect of extracts in dermatophytes fungi cultures with minimum dose (6.25 mg.ml-1) was comparable to a concentration of 10 μg.ml-1 clotrimazole. The findings indicate that the methanolic extract of plants have antifungal effects on the growth of dermatophytes.


Author(s):

Somayeh Farahmand, Azadeh Rasooli, Mehranoush Saffarpour



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