In this study, focused on effect immune cells on bone and directed effect on osteoblast and osteoclast, which are secreted from cytokines and C-reactive protein and express trigger to immune response to continue to cause osteoporosis. Role of humoral immune response to osteoporosis is demonstrated. Some immunological indicators are studies for Iraqi patients. Blood samples are collected from all people (patients and healthy controls) to determine calcium levels, alkaline phosphatase enzyme, Erythrocyte Sedimentation Rate (ESR), Immunoglobulin G (IgG), and Immunoglobulin M (IgM). Results showed an increase in erythrocyte sedimentation rate (48.45) compared with healthy controls (16) as the value of T=16.89. There is a significant difference between patients and healthy controls p<0.001. The high rate of IgG (++) compared with IgM (+). It concludes that osteoporosis has a role in immune diseases and chronic diseases.
Laith B Alhusseini, Ali S Kadhim, Maytham M Alabassi, BA Almayahi